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Antibody Validation of IHC for CAP Compliance

Presenter: Sheron Lear (ASCP)HTL, QIHC
November 10, 2016
10:00 AM PT / 1:00 PM ET

In the decades since the beginning of IHC, validating an antibody has gone thru many changes. Some of these changes have been driven by regulatory agencies such as CAP. The goal of these agencies is to ensure every test and diagnosis for every patient is accurate. The number of cases and slides to be tested is also a changing factor. When conditions change, such as pretreatments, protocols, clones, ready to use versus a concentrate antibody, what do I do? Do I need more testing to verify that my results are the same or better? This webinar will take one thru the steps of validating a new antibody, parallel testing of new shipments of antibodies, new lots of antibodies, and detection systems. Titers, pretreatments, and chromogens will also be discussed. How do I manage the paperwork for this testing?

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